دانلود کتاب Drug Discovery: Practices, Processes, and Perspectives – کشف دارو: شیوه ها، فرآیندها و دیدگاه ها

توضیحات

Sets forth the history, state of the science, and future directions of drug discovery

Edited by Jie Jack Li and Nobel laureate E. J. Corey, two leading pioneers in drug discovery and medicinal chemistry, this book synthesizes great moments in history, the current state of the science, and future directions of drug discovery into one expertly written and organized work. Exploring all major therapeutic areas, the book introduces readers to all facets and phases of drug discovery, including target selection, biological testing, drug metabolism, and computer-assisted drug design.

Drug Discovery features chapters written by an international team of pharmaceutical and medicinal chemists. Contributions are based on a thorough review of the current literature as well as the authors’ firsthand laboratory experience in drug discovery. The book begins with the history of drug discovery, describing groundbreaking moments in the field. Next, it covers such topics as:

• Target identification and validation
• Drug metabolism and pharmacokinetics
• Central nervous system drugs
• In vitro and in vivo assays
• Cardiovascular drugs
• Cancer drugs

Each chapter features a case study, helping readers understand how science is put into practice throughout all phases of drug discovery. References at the end of each chapter serve as a gateway to groundbreaking original research studies and reviews in the field.

Drug Discovery is ideal for newcomers to medicinal chemistry and drug discovery, providing a comprehensive overview of the field. Veterans in the field will also benefit from the perspectives of leading international experts in all aspects of drug discovery.

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ترجمه ماشینی :

تاریخچه، وضعیت علم و مسیرهای آینده کشف دارو را بیان می کند

ویرایش شده توسط جی جک لی و برنده جایزه نوبل EJ Corey، دو پیشگام برجسته در کشف مواد مخدر و شیمی دارویی، این کتاب لحظات بزرگی در تاریخ، وضعیت فعلی علم و مسیرهای آینده کشف دارو را در یک اثر ماهرانه نوشته شده و سازماندهی شده ترکیب می کند. این کتاب با کاوش در تمام زمینه‌های اصلی درمانی، خوانندگان را با تمام جنبه‌ها و مراحل کشف دارو، از جمله انتخاب هدف، آزمایش‌های بیولوژیکی، متابولیسم دارو، و طراحی دارو به کمک رایانه آشنا می‌کند.

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