توضیحات
Our knowledge and understanding of allergic diseases of the respiratory tract has improved to a point where new therapies are being developed for patient benefit.
Inflammation and Allergy Drug Design explains the biologic science that underpins the pathophysiology of asthma and related disorders, as well as their mechanisms. This authoritative guide consists of 25 chapters, each detailing the cutting-edge developments in a particular field. It is divided into three parts, covering cytokines, chemokines, grow factors and mediators.
This book allows immunologists, allergologists and researchers in the pharmaceutical industry to learn and appreciate the target biology in drug development. It also provides medical and pharmaceutical postgraduate
students and clinicians with a basic understanding of allergic diseases in the respiratory tract.
Content:
Chapter 1 Novel Anti?Inflammatory Drugs Based on Targeting Lung Dendritic Cells and Airway Epithelial Cells (pages 114): Bart N. Lambrecht, Maud Plantinga, Monique Willart and Hamida Hammad
Chapter 2 Role of Th2 Cells in the Allergic Diathesis (pages 1525): Marsha Wills?karp
Chapter 3 Importance of Th17? and Th1?Associated Responses for the Development of Asthma (pages 2738): Tomohiro Yoshimoto, Hiroko Tsutsui and Kenji Nakanishi
Chapter 4 Regulatory T Cells (pages 3957): Chris Corrigan and Kimuli Ryanna
Chapter 5 A Role for Natural Killer T?Cell Subsets in the Pathogenesis of Various Allergic Disorders (pages 5966): Hiroshi Watarai, Michishige Harada, Mayumi Tamari and Masaru Taniguchi
Chapter 6 Regulatory Roles of B Cells in Allergy and Inflammation (pages 6777): Kiyoshi Takatsu, Masashi Ikutani and Yoshinori Nagai
Chapter 7 Mast Cells (pages 79105): Mindy Tsai and Stephen J. Galli
Chapter 8 Eosinophils (pages 107121): Nancy A. Lee, Mark V. Dahl, Elizabeth A. Jacobsen and Sergei I. Ochkur
Chapter 9 Basophils in Inflammation and Allergy Drug Design (pages 123137): Donald MacGlashan
Chapter 10 Epithelial Cells (pages 139148): Tillie?Louise Hackett, Stephanie Warner, Dorota Stefanowicz and Darryl Knight
Chapter 11 Fibroblasts (pages 149162): Alastair G. Stewart, Lilian Soon and Michael Schuliga
Chapter 12 Airway Smooth Muscle Cells (pages 163171): Andrew J. Halayko and Pawan Sharma
Chapter 13 Interleukin 4, Interleukin 13, and Interleukin 9 (pages 173185): Kenji Izuhara, Shoichiro Ohta, Hiroshi Shiraishi and Shoichi Suzuki
Chapter 14 Interleukin 3, Interleukin 5, and GranulocyteMacrophage Colony?Stimulating Factor (pages 187196): Alba Llop?Guevara, Josip Marcinko, Ramzi Fattouh and Manel Jordana
Chapter 15 Interleukin 15, Interleukin 17, and Interleukin 25 (pages 197204): Hiroshi Nakajima and Itsuo Iwamoto
Chapter 16 Thymic Stromal Lymphopoietin (pages 205214): Kazuhiko Arima and Yong?Jun Liu
Chapter 17 Interleukin 10 (pages 215224): Whitney W. Stevens, Larry Borish and John W. Steinke
Chapter 18 Tumor Necrosis Factor Alpha (pages 225235): Christopher Brightling, Latifa Chachi, Dhan Desai and Yassine Amrani
Chapter 19 Profibrotic and Angiogenic Factors in Asthma (pages 237252): Neville Berkman and Francesca Levi?Schaffer
Chapter 20 Chemokines (pages 253261): Luis M. Teran and Juan R. Velazquez
Chapter 21 Epithelial Growth Factors (pages 263270): Yasuhiro Gon and Shu Hashimoto
Chapter 22 Prostanoids (pages 271283): Sarah A. Maher, Deborah L. Clarke and Maria G. Belvisi
Chapter 23 Leukotrienes (pages 285295): Katsuhide Okunishi and Marc Peters?Golden
Chapter 24 Proteases in Allergy (pages 297305): Keisuke Oboki and Hirohisa Saito
Chapter 25 Toll?Like Receptors (pages 307316): Jessica L. Allen, Aurelien Trompette and Christopher L. Karp
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ترجمه ماشینی :
دانش و درک ما از بیماریهای آلرژیک دستگاه تنفسی تا جایی بهبود یافته است که روشهای درمانی جدید به نفع بیمار انجام می شود. B> علم بیولوژیکی را که زیربنای پاتوفیزیولوژی آسم و اختلالات مرتبط با آن و همچنین مکانیسم های آنها است ، توضیح می دهد. این راهنمای معتبر از 25 فصل تشکیل شده است که هر یک از آنها در یک زمینه خاص ، پیشرفت های برجسته را نشان می دهد. این کتاب به سه بخش تقسیم می شود و سیتوکین ها ، شیمیایی ، فاکتورهای رشد و واسطه ها را پوشش می دهد. همچنین دانش آموزان
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